As per a small US study, Budesonide (a steroid nasal wash) can prove to be a highly effective option for reducing the symptoms of chronic sinusitis without affecting functions of the adrenal gland.
Chronic Sinusitis can be classified as a continuing inflammation of the nose and sinuses behind it that tend to affect approximately 14 percent population of the United States alone.
It was remarked by researchers from the Washington University School of Medicine in St. Louis that this first-of-its-kind study suggested that suppression of the functions of the adrenal gland is a known complication of Budesonide.
From Bio-Medicine.Org:
All participants reported at least some improvement in their sinusitis symptoms, and their adrenal gland function was not affected, the study found. The results were published in the March issue of Otolaryngology — Head & Neck Surgery.
“The clinical significance of this study is that budesonide nasal respules appear safe for short-term use for the relief of symptoms associated with chronic sinusitis,” the researchers concluded. “Budesonide respules seem to provide an effective treatment option for the patient with chronic rhinosinusitis with minimal fear of systemic adverse effects.”
The drug is presently awaiting FDA approval, which means that the nasal wash of this study would be an off-label use of the drug.
In the meanwhile, the involved researchers have advised medical fraternity to be very careful in advising patients about the possible risks associated with long-term use of Budesonide such as decreased bone mineral density.

